Sermorelin essentially mimics the hypothalamic peptide, GHRH. Sermorelin acts directly on the pituitary stimulating the somatotroph cells ability to produce and secrete GH. Sermorelin increases proliferation of somatotroph cells during development. With the increase of serum GH, downstream effects occur. A notable hormone that is commonly used as a surrogate for growth hormone therapy, insulin like growth factor 1 (IGF-1), is known to increase with the administration of Sermorelin. IGF-I negatively regulates GHRH-mediated GH secretion
NAD and NAD+ occur naturally in the body. They play a major role in the chemical process of generating energy. NAD+ is probably the most important co-factor for improving mitochondrial function. Mitochondria are intracellular organelles (AKA “energy powerhouses”) where micronutrients are converted to energy-rich ATP molecules for the cell. As we age, our body’s NAD levels gradually drop due to lower intrinsic production and inflammation/oxidative stress caused by environmental factors. This drop in NAD+ can cause fatigue, mental fog, dull and tired skin, and poor sleep quality. Boosting NAD+ may help manage a wide spectrum of diseases, ranging from diabetes to cancer.
NAD+ can be administered via IV (intravenous), IM (intramuscular), or SC (subcutaneous) route. When administered by IV, some research has demonstrated its ability to improve mental clarity, memory, concentration and alertness. Moreover, NAD+ infusions may improve athletic endurance and reverse the symptoms of chronic fatigue.
Research has shown that NAD+ may have potential for fighting the effects of addiction. Excessive alcohol and drug use diminishes the amount of NAD naturally found in the body; by reintroducing it through NAD therapy, cravings and withdrawal effects may be reduced as a result. Additionally, NAD+ has been shown to boost serotonin, aiding with symptoms brought on by depression and anxiety.
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